An integrated multi-omics analysis of the NK603 Roundup-tolerant GM maize reveals metabolism disturbances caused by the transformation process : Scientific Reports

Glyphosate tolerant genetically modified (GM) maize NK603 was assessed as ‘substantially equivalent’ to its isogenic counterpart by a nutrient composition analysis in order to be granted market approval.

We have applied contemporary in depth molecular profiling methods of NK603 maize kernels (sprayed or unsprayed with Roundup) and the isogenic corn to reassess its substantial equivalence status.

Proteome profiles of the maize kernels revealed alterations in the levels of enzymes of glycolysis and TCA cycle pathways, which were reflective of an imbalance in energy metabolism. Changes in proteins and metabolites of glutathione metabolism were indicative of increased oxidative stress. The most pronounced metabolome differences between NK603 and its isogenic counterpart consisted of an increase in polyamines including N-acetyl-cadaverine (2.9-fold), N-acetylputrescine (1.8-fold), putrescine (2.7-fold) and cadaverine (28-fold), which depending on context can be either protective or a cause of toxicity.

Our molecular profiling results show that NK603 and its isogenic control are not substantially equivalent.

Source: An integrated multi-omics analysis of the NK603 Roundup-tolerant GM maize reveals metabolism disturbances caused by the transformation process : Scientific Reports

Cumberland adopts a Preferential Non GMO Purchase Policy

Cumberland  adopts a Preferential Non GMO purchase policy.  

Local food !

Cumberland, you rock!

Leading the way to a healthier community, on Nov 28th 2016 , Cumberland  Council added to their Section 6 Sustainable Procurement Practices, that “The Village does not support the purchase of genetically modified (GM0) apples and salmon; and for all other products, the Village prefers to purchase non-genetically modified products where reasonable”.  

The policy will help support local organic producers, who must compete with big box stores and allow Cumberland to play its part in increasing local self sufficiency and food independence. This policy is similar to one adopted by the City of Duncan in 2014.  

Linda Safford, a GE Free Comox Valley member notes,“Many business owners in Cumberland were supportive of this initiative.  We are glad that Cumberland Village council and staff are implementing socially progressive policies.“ 

Countless surveys have shown that the Canadian public wants mandatory labelling of genetically modified products yet Health Canada continues to approve the selling of unlabelled GM products, such as GM Salmon and the GM non-browning apple.  By introducing the preferential non GM product purchasing policy, Cumberland and other GE Free zone municipalities show that they will step up to protect community interest, through the use of purchasing power, even if Ottawa will not.  

Rick Dobson, a local business owner, says, “I am really proud that my Village has taken a leadership role to support a preferential non-GMO policy.  And I hope that Courtenay and Comox will join Cumberland to promote buying non-genetically modified products.  And let’s buy local and organic”. 

 The Village of Cumberland,BC is on Vancouver Island.